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What the Research Is Telling Us Two studies from 2024 have raised big red flags: A study published in JAMA Ophthalmology found that semaglutide users were over four times more likely to develop NAION than those on other diabetes drugs

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Reduced ATP production and impaired mitochondrial function were observed not only in the lungs, but also in the heart and other tissues

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Researchers noted that more research is needed into specific types of melatonin and dosages to ensure safety